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Contrary to general belief, the matter content of the Universe is not dominated by dark matter particles. This is shown by a number of tests using modern astrophysical data all of which lead to mutually consistent conclusions. This implies that the dark-matter-based cosmological models are not relevant for accounting for the observed cosmological structures and their time evolution. I will outline our steps towards a comprehensive non-dark-matter (and non-dark-energy) based cosmological model which have matured to simulations of structure formation that appear to be consistent also with the JWST observations of galaxies at redshifts larger than 10.